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A Microfluidic Device With Concave Surfaced Micropost Array for Rare Cell Capture
- Issue Date
- Jan-2014
- Publisher
- IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
- Keywords
- Concave micropost; microfluidics; capture rate; cell capture
- Citation
- IEEE SENSORS JOURNAL, v.14, no.1, pp 5 - 6
- Pages
- 2
- Journal Title
- IEEE SENSORS JOURNAL
- Volume
- 14
- Number
- 1
- Start Page
- 5
- End Page
- 6
- ISSN
- 1530-437X
1558-1748
- Abstract
- Microfluidic devices are becoming a standard method of lab analysis of many different types of samples. This letter presents a uniquely shaped micropost structure set in an arrayed fashion for sensing and cell capture purposes. After simulating the design to confirm its improved functionality, a model cell line was used to determine the capture yield and capture rate of the device. Specific capture was achieved by coating the array of microposts with antibodies that target the epithelial cell adhesion molecule, a common biomarker for many types of metastatic cancer.
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Collections - College of Natural Sciences > Department of Life Science > 1. Journal Articles
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