대용량의 Haplotype과 Genotype데이터에 대한 LD기반의 tagSNP 선택 시스템
- Authors
- 김상준; 여상수; 김성권
- Issue Date
- Nov-2004
- Citation
- 한국생물정보학회 학술발표회집, pp 279 - 285
- Pages
- 7
- Journal Title
- 한국생물정보학회 학술발표회집
- Start Page
- 279
- End Page
- 285
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/60365
- Abstract
- In the disease association study, the tagSNP selection problem is important at the view of time and cost. We developed the new tagSNP selection system that has also facilities for the haplotype reconstruction and missing data processing. In our system, we improved biological meanings using LD coefficients as well as dynamic programming method. And our system has capability of processing large -scale dataset, such as the total SNPs on a chromosome. We have tested our system with various dataset from daly et al., patil et al., HapMap Project, artificial dataset, and so on.
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