Relationship between Binocular Visual Function and Quality of Life in Bilateral Normal Tension Glaucoma Patients

Abstract

목적: 양안 정상안압녹내장 환자에서 입체시와 대비감도의 감소가 삶의 질에 미치는 영향을 분석하고, 통합된 두 눈 시야와 시기능사이의 연관성을 알아보고자 하였다. 대상과 방법: 양안 정상안압녹내장으로 진단 받은 환자 44명과 정상 대조군 32명을 대상으로 입체시, 대비감도 검사를 시행하고, 각눈의 시야를 Best location 방법으로 통합하여 두 눈 시야를 구현하였다. 삶의 질을 평가하기 위한 한국어판 미국 국립안연구센터시각 기능 설문지의 세부 항목과 각각의 검사 결과 간의 연관성은 단변량 선형회귀분석으로 평가하였다. 결과: 양안 정상안압녹내장 환자의 입체시와 대비감도는 정상 대조군에 비해 유의하게 감소하였으며, 이러한 시기능의 감소는 시각기능설문지로 측정된 삶의 질 항목 중 시각과 관련된 사회적 기능과 색각에서 유의한 상관관계를 보였다. 통합된 두 눈 시야의 mean deviation (MD)과 좋은 쪽 눈 MD는 입체시와 대비감도 모두와 의미 있는 연관성을 보였지만, 나쁜 쪽 눈 MD는 연관성을 보이지 않았다. 결론: 정상안압녹내장 환자에서 감소된 입체시와 대비감도는 시각과 관련된 사회적 기능과 색각과 관련된 삶의 질에 영향을 미치며, 통합된 두 눈 시야와 좋은 쪽 눈의 MD는 환자의 입체시, 대비감도와 유의한 상관관계를 보인다.

Purpose: To analyze the effect of stereopsis and contrast sensitivity on the quality of life and to evaluate the relationship between integrated binocular visual field (IVF) and binocular visual function in bilateral normal tension glaucoma (NTG) patients. Methods: Stereopsis and contrast sensitivity tests were performed and compared among 44 NTG patients and 32 normal subjects. The IVF was integrated using the best location method. The correlation between visual function and subscales of the National Eye Institute Visual Function Questionnaire 25 (NEI VFQ-25) was evaluated using univariate linear regression. Results: Stereopsis and contrast sensitivity for the bilateral NTG patients were decreased compared to the normal controls. Stereopsis and contrast sensitivity exhibited a significant correlation with social functions related to vision and color vision among subscales of NEI VFQ-25. IVF mean deviation (MD) and better eye MD showed a significant correlation with stereopsis and contrast sensitivity, while worse eye MD showed no association. Conclusions: Deterioration of stereopsis and contrast sensitivity in NTG patients affects their quality of life related to social functions and color vision. Both IVF and better eye MDs are correlated with stereopsis and contrast sensitivity in NTG patients.

Purpose: To analyze the effect of stereopsis and contrast sensitivity on the quality of life and to evaluate the relationship between integrated binocular visual field (IVF) and binocular visual function in bilateral normal tension glaucoma (NTG) patients. Methods: Stereopsis and contrast sensitivity tests were performed and compared among 44 NTG patients and 32 normal subjects. The IVF was integrated using the best location method. The correlation between visual function and subscales of the National Eye Institute Visual Function Questionnaire 25 (NEI VFQ-25) was evaluated using univariate linear regression. Results: Stereopsis and contrast sensitivity for the bilateral NTG patients were decreased compared to the normal controls. Stereopsis and contrast sensitivity exhibited a significant correlation with social functions related to vision and color vision among subscales of NEI VFQ-25. IVF mean deviation (MD) and better eye MD showed a significant correlation with stereopsis and contrast sensitivity, while worse eye MD showed no association. Conclusions: Deterioration of stereopsis and contrast sensitivity in NTG patients affects their quality of life related to social functions and color vision. Both IVF and better eye MDs are correlated with stereopsis and contrast sensitivity in NTG patients.