Tuning Local Coordination Environments of Manganese Single-Atom Nanozymes with Multi-Enzyme Properties for Selective Colorimetric Biosensing
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wang, Y. | - |
dc.contributor.author | Cho, A. | - |
dc.contributor.author | Jia, G. | - |
dc.contributor.author | Cui, X. | - |
dc.contributor.author | Shin, J. | - |
dc.contributor.author | Nam, I. | - |
dc.contributor.author | Noh, K.-J. | - |
dc.contributor.author | Park, B.J. | - |
dc.contributor.author | Huang, R. | - |
dc.contributor.author | Han, J.W. | - |
dc.date.accessioned | 2023-03-08T04:48:07Z | - |
dc.date.available | 2023-03-08T04:48:07Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.issn | 1521-3773 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/61119 | - |
dc.description.abstract | Single-atom nanozymes (SAzymes) are promising in next-generation nanozymes, nevertheless, how to rationally modulate the microenvironment of SAzymes with controllable multi-enzyme properties is still challenging. Herein, we systematically investigate the relationship between atomic configuration and multi-enzymatic performances. The constructed MnSA−N3-coordinated SAzymes (MnSA−N3−C) exhibits much more remarkable oxidase-, peroxidase-, and glutathione oxidase-like activities than that of MnSA−N4−C. Based on experimental and theoretical results, these multi-enzyme-like behaviors are highly dependent on the coordination number of single atomic Mn sites by local charge polarization. As a consequence, a series of colorimetric biosensing platforms based on MnSA−N3−C SAzymes is successfully built for specific recognition of biological molecules. These findings provide atomic-level insight into the microenvironment of nanozymes, promoting rational design of other demanding biocatalysts. © 2023 Wiley-VCH GmbH. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | John Wiley and Sons Inc | - |
dc.title | Tuning Local Coordination Environments of Manganese Single-Atom Nanozymes with Multi-Enzyme Properties for Selective Colorimetric Biosensing | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/anie.202300119 | - |
dc.identifier.bibliographicCitation | Angewandte Chemie - International Edition, v.62, no.15 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000942304000001 | - |
dc.identifier.scopusid | 2-s2.0-85149069084 | - |
dc.citation.number | 15 | - |
dc.citation.title | Angewandte Chemie - International Edition | - |
dc.citation.volume | 62 | - |
dc.type.docType | Article | - |
dc.publisher.location | 독일 | - |
dc.subject.keywordAuthor | Biocatalyst | - |
dc.subject.keywordAuthor | Biosensing | - |
dc.subject.keywordAuthor | Coordination Environment | - |
dc.subject.keywordAuthor | Multi-Enzyme Properties | - |
dc.subject.keywordAuthor | Single-Atom Nanozyme | - |
dc.subject.keywordPlus | CATALYSTS | - |
dc.subject.keywordPlus | DEFECTS | - |
dc.subject.keywordPlus | WAVE | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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