Short-term Effect of Gamma Knife Radiosurgery for a Choroidal Tumor
- Authors
- Lee, Ko Eun; Yeo, Joon Hyung; Kim, Yoon Jeon; Kim, June Gone; Yoon, Young Hee; Kwon, Do Hoon; Cho, Young Hyun; Lee, Joo Yong
- Issue Date
- Oct-2020
- Publisher
- KOREAN OPHTHALMOLOGICAL SOC
- Keywords
- Choroidal melanoma; Choroidal metastasis; Gamma knife radiosurgery
- Citation
- JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, v.61, no.10, pp 1156 - 1163
- Pages
- 8
- Journal Title
- JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY
- Volume
- 61
- Number
- 10
- Start Page
- 1156
- End Page
- 1163
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/63207
- DOI
- 10.3341/jkos.2020.61.10.1156
- ISSN
- 0378-6471
2092-9374
- Abstract
- Purpose: To evaluate the effectiveness and safety of treating choroidal melanoma and cancer that has metastasized to the choroid with gamma knife radiosurgery (GKR). Methods: We performed a retrospective chart review that included 10 eyes of eight patients with a diagnosis of choroidal tumors who underwent GKR between January 2016 and February 2019 and who had at least one month follow-up visit. Results: The mean patient age was 57.9 +/- 14.6 years (range, 32-83 years). The choroidal tumor group included six choroidal metastases and four choroidal melanomas. The mean follow-up period after GKR was 7.0 +/- 4.3 months (range, 2-13 months). The mean cumulative marginal dose was 25.36 +/- 7.35 Gy (range, 16-45 Gy). Pre- and postoperative magnetic resonance imaging revealed a reduction in tumor volume in eight of the 10 eyes and five of them presented with improved visual symptoms. One patient showed increased tumor volume; however, a new choroidal lesion was not observed. Another patient showed no reduction in tumor size; however, the pain had worsened, and the eye was enucleated. The mean maximum tumor diameter decreased from 1.60 +/- 0.37 cm before to 1.22 +/- 0.47 cm after GKR (p = 0.004), and the mean minimum diameter decreased from 0.62 +/- 0.27 cm before to 0.38 +/- 0.35 cm after GKR (p = 0.031). No radiation-induced optic neuropathy, retinopathy, or cataracts was observed in any of the cases during the follow-up period. Conclusions: GKR was shown to be safe for choroidal lesions identified in orbital magnetic resonance imaging with a reduction in the size of choroidal tumors and eyeball preservation expected with this treatment approach.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > College of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/63207)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.