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Surface-enhanced Raman scattering in picoliter droplets: Towards highly sensitive and selective detection of mercury ions
- Authors
- Lim C.; Ko J.; Wang G.; Chen L.; DeMello A.J.; Hong J.; Choo, Jaebum
- Issue Date
- Nov-2009
- Publisher
- Chemical and Biological Microsystems Society
- Keywords
- Aptamer; Lab on a Chip; Microdroplet; SERS; Trace analysis
- Citation
- Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp 326 - 328
- Pages
- 3
- Journal Title
- Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- Start Page
- 326
- End Page
- 328
- ISSN
- 0000-0000
- Abstract
- We report a new method for the trace analysis of mercury ions in water using the droplet-based microfluidics combined with surface-enhanced Raman scattering detection. Specifically, mercury ion detection is performed by using silver nanoparticles labeled with aptamers and Raman reporters. To allow both reproducible and quantitative analysis, a microdroplet channel was used. The manipulation of aqueous droplets through winding microfluidic channels affords rapid and efficient mixing of the contents. This novel combination provides both fast and selective detection of mercury ions in water. © 2009 CBMS.
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