Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
Development of a hybrid scaffold and a bioreactor for cartilage regeneration
- Authors
- Lee, Seung-Jae; Lee, In Hwan; Park, Jeong Hun; Gwak, So-Jung; Rhie, Jong-Won; Cho, Dong-Woo; Ko, Tae Jo; Kim, Dong Sung
- Issue Date
- Oct-2009
- Publisher
- SCIENCE PRESS
- Keywords
- cartilage; scaffold; bioreactor; alginate; agarose
- Citation
- CHINESE SCIENCE BULLETIN, v.54, no.19, pp 3608 - 3612
- Pages
- 5
- Journal Title
- CHINESE SCIENCE BULLETIN
- Volume
- 54
- Number
- 19
- Start Page
- 3608
- End Page
- 3612
- ISSN
- 1001-6538
1861-9541
- Abstract
- We developed a hybrid scaffold and a bioreactor for cartilage regeneration. The hybrid scaffold was developed as combination of two components: a biodegradable framework and hydrogel-containing chondrocytes. We performed the MTT cell proliferation assay to compare the proliferation and viability of chondrocytes on three types of scaffolds: an alginate gel, the hybrid scaffold, and an alginate sponge. Cells were encapsulated in 2% agarose gel. The bioreactor consisted of a circulation system and a compression system. We performed dynamic cell culture on these agarose gels in the bioreactor for 3 days.
- Files in This Item
- Appears in
Collections - College of Engineering > School of Mechanical Engineering > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.