Functionalization of Gold Nanostars with Melamine for Colorimetric Detection of Uric Acid
- Authors
- Dandu, S.S.; Joshi, D.J.; Park, Tae Jung; Kailasa, S.K.
- Issue Date
- Apr-2023
- Publisher
- SAGE Publications Inc.
- Keywords
- biofluids; DLS; dynamic light scattering; FE-SEM; field emission scanning electron microscopy; Gold nanostars; uric acid; UV–Vis; UV–Visible spectroscopy
- Citation
- Applied Spectroscopy, v.77, no.4, pp 360 - 370
- Pages
- 11
- Journal Title
- Applied Spectroscopy
- Volume
- 77
- Number
- 4
- Start Page
- 360
- End Page
- 370
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/66352
- DOI
- 10.1177/00037028231154935
- ISSN
- 0003-7028
1943-3530
- Abstract
- Gold nanostars (AuNSs) are synthesized using a seed-mediated growth method. The synthesized AuNSs solution is stable and shows a localized surface plasmon resonance (LSPR) band in the visible range, which is confirmed using ultraviolet–visible (UV–Vis) spectroscopy. Furthermore, the as-synthesized AuNSs were functionalized with melamine and used as a sensor for the colorimetric detection of uric acid (UA). The detection mechanism could be assessed through various analytical techniques such as UV–Vis spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, dynamic light scattering (DLS), zeta potential, field emission scanning electron microscopy (FE-SEM), and transmission electron microscopic techniques. These methods exhibited a good linear regression between the absorption ratio of LSPR band of melamine–AuNSs and the concentration of UA (0–120 µM), with the detection limit of 8.50 nm. As a result, UA was quantitatively detected in biofluids by using melamine-AuNSs as a colorimetric sensor, revealing melamine–AuNSs–based colorimetric approach which could be used as a simple platform for UA assay in biofluids. © The Author(s) 2023.
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Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
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