기저세포암종의 병리학적 분석

Abstract

Though basal cell carcinoma is the most frequent and increasing malignant tumor of the skin in Korea, its pathological analysis has been done only on the small numbers. So, we did a comprehensive pathologic study on the 283 patients with basal cell carcinoma di- agnosed in the Department of Pathology, Seoul National (233cases) and Chung-Ang(50cases) Uni- versity Hospital during 1975-1992. The age distribution was ranged from 15 to 84 years with highest incidence rate in the age group of 5th-8th decades and 83.7% of all patients were over 40 years of age. Sex difference was not noted. The most common site was face occuring in 235 out of 283cases(83.0%) especially in the eyelid (25.5%), nose (17.9%) and cheek(16.6%). The most frequent histopathologic type was solid type (54.0%) followed by mixed(23.9%), adenoid (7.5% ), and metatypical (4.7%). Among 51 mixed type, all showed solid components with adenoid (51.0%) followed by morphea(25.5%) and metatypical type(13.7%). And among 14 recurrent cases, solid type is found in 50% of cases. The characteristic clinicopathological findings are solid arrangement of tumor cells with various his- tological pattern and predominant occurence on the face.