혈액 내 구리, 아연 및 ceruloplasmin 농도에 흡연, 음주 및 신체적 활동이 미치는 영향The Influence of Smoking, Alcohol Ingestion, and Physical Activity on Copper, Zinc and Ceruloplasmin in Blood of Male Adults
- Authors
- 박진완; 강은용; 신인철; 최병선; 박정덕; 장임원; 홍연표
- Issue Date
- Dec-1999
- Publisher
- 대한산업의학회
- Keywords
- Alcohol intake; Ceruloplasmin; Copper; Zinc, Smoking; Physical activity
- Citation
- 대한산업의학회지, v.11, no.4, pp 569 - 578
- Pages
- 10
- Journal Title
- 대한산업의학회지
- Volume
- 11
- Number
- 4
- Start Page
- 569
- End Page
- 578
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/66621
- Abstract
- Objective To investigate the influence of smoking, alcohol ingestion, and physical activity on copper and zinc in RBC and serum and serum ceruloplasmin, this study was performed in a cross-sectional study in 113 healthy men aged 20 to 40 years who had no symptomatic liver, heart, gastrointestinal, and other chronic diseases.
Methods At the men's entry into the study, blood samples were drawn from each subject and immediately centrifuged for analysis of copper, zinc, iron, ceruloplasmin, total cholesterol, and hematocrit. Each man completed a questionnaire that provided information on smoking, amount of alcohol intake, and physical activity. Partial regres- sion analysis was performed on confounding variables such as age, body mass index, hematocrit, serum cholesterol, and serum iron.
Results: In general linear models, adjustment for confounding variables did not show statistical differences, and there was only an increasing tendency in serum copper in heavy smoker (P-0.0678). There was no difference between high physical activity with mild smokers and lower physical activity with heavy smokers.
Conclusions: This study suggested that copper, zinc and ceruloplasmin were not good biomarker for early effect by smoking, alcohol intake and physical activity in young adult. However, selection bias should be considered in evaluation of this result, and a large prospective study will be needed in advance on usefulness of copper, zinc and ceru- loplasmin as a marker for risk factors and early change of atherosclerosis.
- Files in This Item
-
Go to Link
- Appears in
Collections - College of Medicine > College of Medicine > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.