백리향 지상부로부터 얻은 정유와 에탄올추출물의 성분 및 항산화활성

Abstract

Thymus quinquecostatus Celak. (TQC) has high antioxidant activity. To identify the functional compounds, TQC was extracted as essential oils and an ethanol (EtOH) extract. TQC essential oils and EtOH extract was extracted via steam distillation and heat reflux extractor, respectively. Gas chromatography/mass spectrometry of TQC essential oils revealed that thymol, o-cymene, linalool, and γ-terpinene contributed approximately 57% of the total composition of TQC. High-performance liquid chromatography/photodiode array revealed that caffeic acid (CA) and rosmarinic acid (RA) were associated with the antioxidant activity of TQC. Moreover, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 2,2-diphenyl-1-picrylhydrazyl radical-scavenging assays were performed to determine the activities of TQC essential oils, EtOH extract, CA and RA. TQC EtOH extract tends to show high antioxidant activity against both radicals. Furthermore, CA and RA showed outstanding radical-scavenging activities, compared to ascorbic acid. Therefore, CA and RA could assist the biologically activities of TQC. Our findings suggest that TQC is suitable for medicinal use as a natural product.