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Screening of aldose reductase inhibitory activities of Korean folk plants in Chungcheong Province
- Authors
- Lee, D.G.; Lee, K.H.; Choi, K.; Ku, J.; Park, K.-W.; Cho, E.J.; Lee, Sanghyun
- Issue Date
- Mar-2013
- Publisher
- Institute of Agricultural Science, CNU
- Keywords
- Aldose reductase inhibition; Diabetic complications; Folk plant; Persicaria longiseta
- Citation
- Korean Journal of Agricultural Science, v.40, no.1, pp 47 - 51
- Pages
- 5
- Journal Title
- Korean Journal of Agricultural Science
- Volume
- 40
- Number
- 1
- Start Page
- 47
- End Page
- 51
- ISSN
- 2466-2402
2466-2410
- Abstract
- To search for the aldose reductase (AR) inhibitors from Korean folk plants, the inhibition of rat lens AR in vitro using the methanol (MeOH) extracts from Korean folk plants in Chungcheong Province was investigated. Among Korean folk plants tested, the MeOH extract of Persicaria longiseta showed highest inhibition of AR (IC50 value, 5.14μg/ml). Consequently, P. longiseta has a possibility of new natural resources for the development of AR inhibitor for the prevention of diabetic complications.
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