Effects of gypenoside L-containing Gynostemma pentaphyllum extract on fatigue and physical performance: A double-blind, placebo-controlled, randomized trial
DC Field | Value | Language |
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dc.contributor.author | Ahn, Yejin | - |
dc.contributor.author | Lee, Hee-Seok | - |
dc.contributor.author | Lee, Seok-Hee | - |
dc.contributor.author | Joa, Kyung-Lim | - |
dc.contributor.author | Lim, Cho Young | - |
dc.contributor.author | Ahn, Yu Jin | - |
dc.contributor.author | Suh, Hyung Joo | - |
dc.contributor.author | Park, Sung-Soo | - |
dc.contributor.author | Hong, Ki-Bae | - |
dc.date.accessioned | 2024-01-08T21:34:21Z | - |
dc.date.available | 2024-01-08T21:34:21Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 0951-418X | - |
dc.identifier.issn | 1099-1573 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/69566 | - |
dc.description.abstract | This study was conducted to investigate the effect of Gynostemma pentaphyllum extract containing gypenoside L (GPE) on improving the cognitive aspects of fatigue and performance of the motor system. One hundred healthy Korean adults aged 19-60 years were randomized to the treatment (GPE for 12 weeks) and control groups, and efficacy and safety-related parameters were compared between the two groups. Maximal oxygen consumption (VO2 max) and O-2 pulse were significantly higher in the treatment group than in the control group (p = 0.007 and p = 0.047, respectively). After 12 weeks, the treatment group showed significant changes such as decreases in the levels of free fatty acids (p = 0.042). In addition, there were significant differences in the rating of perceived exertion (RPE) (p < 0.05) and value of temporal fatigue between the treatment and control groups on the multidimensional fatigue scale (p < 0.05). Moreover, the level of endothelial nitric oxide synthase (eNOS) in the blood was significantly higher in the treatment group than in the control group (p = 0.047). In summary, oral administration of GPE has a positive effect on resistance to exercise-induced physical and mental fatigue. | - |
dc.format.extent | 14 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY | - |
dc.title | Effects of gypenoside L-containing Gynostemma pentaphyllum extract on fatigue and physical performance: A double-blind, placebo-controlled, randomized trial | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/ptr.7801 | - |
dc.identifier.bibliographicCitation | PHYTOTHERAPY RESEARCH, v.37, no.7, pp 3069 - 3082 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000943787400001 | - |
dc.identifier.scopusid | 2-s2.0-85149700285 | - |
dc.citation.endPage | 3082 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 3069 | - |
dc.citation.title | PHYTOTHERAPY RESEARCH | - |
dc.citation.volume | 37 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | clinical trial | - |
dc.subject.keywordAuthor | cognitive fatigue | - |
dc.subject.keywordAuthor | exercise performance | - |
dc.subject.keywordAuthor | Gynostemma pentaphyllum | - |
dc.subject.keywordAuthor | gypenoside L | - |
dc.subject.keywordPlus | NF-KAPPA-B | - |
dc.subject.keywordPlus | EXERCISE PERFORMANCE | - |
dc.subject.keywordPlus | ACID-METABOLISM | - |
dc.subject.keywordPlus | MUSCLE FATIGUE | - |
dc.subject.keywordPlus | LACTIC-ACID | - |
dc.subject.keywordPlus | SUPPLEMENTATION | - |
dc.subject.keywordPlus | CURCUMIN | - |
dc.subject.keywordPlus | GINSENG | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | QUERCETIN | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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