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Cancer cell imaging by stable wet near-field scanning optical microscope with resonance tracking method
- Authors
- Park, Kyoung-Duck; Park, Doo Jae; Jeong, Mun Seok; Choi, Geun Chang; Lee, Seung Gol; Byeon, Clare Chisu; Choi, Soo Bong
- Issue Date
- May-2014
- Publisher
- KOREAN PHYSICAL SOC
- Keywords
- NSOM; Topography; Nano imaging; Bio imaging; Optical property
- Citation
- JOURNAL OF THE KOREAN PHYSICAL SOCIETY, v.64, no.10, pp 1500 - 1503
- Pages
- 4
- Journal Title
- JOURNAL OF THE KOREAN PHYSICAL SOCIETY
- Volume
- 64
- Number
- 10
- Start Page
- 1500
- End Page
- 1503
- ISSN
- 0374-4884
1976-8524
- Abstract
- We report on a successful topographical and optical imaging of various cancer cells in liquid and in air by using a stable wet near-field scanning optical microscope that utilizes a resonance tracking method. We observed a clear dehydration which gives rise to a decrease in the cell volume down to 51%. In addition, a micro-ball lens effect due to the round-shaped young cancer cells was observed from near-field imaging, where the refractive index of young cancer cells was deduced.
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