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Water-Soluble Red Pigment Production by Paecilomyces sinclairii and Biological Characterization

Authors
Choi, Jang WonPark, Jong Pil
Issue Date
Mar-2018
Publisher
KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING
Keywords
natural pigment; Paecilomyces sinclairii; antimicrobial activity; fractionation; chemical structure
Citation
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.23, no.2, pp 246 - 249
Pages
4
Journal Title
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING
Volume
23
Number
2
Start Page
246
End Page
249
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70193
DOI
10.1007/s12257-018-0103-1
ISSN
1226-8372
1976-3816
Abstract
Natural pigments have several advantages over synthetic colorants. In this study, the production of red pigment produced by Paecilomyces sinclairii in microbial fermentation was demonstrated and the pigment was purified and characterized. The red pigment was produced from submerged fungal fermentation and fractionated by medium pressure flash chromatography. After fractionation, the spectrophotometric characterization of the red pigment revealed an lambda(max) at 520 nm. Antimicrobial activity of the red pigment fraction was also studied against Escherichia coli O157 and Pseudomonas aeruginosa PAO1. The fraction (F2-F6) of the red pigment exhibited broad-spectrum antimicrobial activity in both bacteria. These results demonstrate the potential of this pigment in inhibiting bacterial growth and in food processing and other foodrelated applications.
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대학원 (식품생명공학과)
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