Comparison of Visceral Fat Measures with Cardiometabolic Risk Factors in Healthy Adults
- Authors
- Pak, Kyoungjune; Lee, Seung Hun; Lee, Jeong Gyu; Seok, Ju Won; Kim, In Joo
- Issue Date
- Apr-2016
- Publisher
- PUBLIC LIBRARY SCIENCE
- Citation
- PLOS ONE, v.11, no.4
- Journal Title
- PLOS ONE
- Volume
- 11
- Number
- 4
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/7042
- DOI
- 10.1371/journal.pone.0153031
- ISSN
- 1932-6203
- Abstract
- We aimed to evaluate the associations of visceral adiposity with cardiometabolic risk factors in normal subjects with integrated F-18-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT). A total of 58 normal subjects who underwent F-18-FDG PET/CT scan for cancer screening were included in this study. Volume and average Hounsfield unit (HU) of visceral adipose tissue (VAT) was measured from CT components of integrated PET/CT. Standardized uptake values (SUVmax) of liver, spleen, lumbar spine and ascending aorta (AA) were measured from PET components of integrated PET/CT. Body mass index (coefficient 78.25, p = 0.0259), glucose (37.62, p<0.0001), insulin (348.90, p = 0.0011), logarithmic transformation of homeostatic model assessment indexinsulin resistance (-2118.37, p = 0.0007), and VAT HU (-134.99, p<0.0001) were independently associated with VAT volume. Glucose (0.1187, p = 0.0098) and VAT volume (-0.004, p<0.0001) were found to be associated with VAT HU. Both VAT volume and VAT HU of whole abdominal cavity is significantly associated with cardiometabolic risk factors.
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