Pulmonary Sclerosing Pneumocytoma of the Lung: CT Characteristics in a Large Series of a Tertiary Referral Centeropen access
- Authors
- Shin, So Youn; Kim, Mi Young; Oh, Sang Young; Lee, Hyun Joo; Hong, Soon Auck; Jang, Se Jin; Kim, Sung-Soo
- Issue Date
- Jan-2015
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Citation
- MEDICINE, v.94, no.4
- Journal Title
- MEDICINE
- Volume
- 94
- Number
- 4
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70563
- DOI
- 10.1097/MD.0000000000000498
- ISSN
- 0025-7974
1536-5964
- Abstract
- The purpose of this study is to describe the detailed clinical, chest computed tomography (CT), and F-18-fluorodeoxyglucose positron emission tomography (FDG PET) characteristics of the tumor boundary for the diagnosis and investigate the outcome of pulmonary sclerosing pneumocytoma (PSP) using confirmed large data of a tertiary referral center. Confirmed 76 patients were included. We evaluated the findings of CT including 4 CT signs, FDG PET, and histopathology. Most patients had a single lesion (92.1%), smooth boundary (65.8%), and oval shape (65.8%) and the mean diameter was 22.7 mm. The CT signs included marginal pseudocapsule (50%), overlying vessel (26.3%), air gap (2.6%), and halo sign (17.1%). A predominantly solid was the most common histopathologic type. The mean maximum standardized uptake value on FDG PET of 17 patients was 1.8 (range, near 0 or normal tissue metabolism similar to 2.9). PSP should be considered in middle-aged women whose CT features show incidental nodule(s), commonly with surrounding ground-glass opacity and characteristic CT signs of the tumor boundary, and hypometabolic uptake on FDG PET. Outcome of patients is excellent.
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