Carbonylative ring expansion of oxetane into γ-butyrolactone using bimetallic cobaltate catalysts: Insight into the deactivation mechanism
- Authors
- Ganesan, Vinothkumar; Yoon, Sungho
- Issue Date
- Dec-2023
- Publisher
- John Wiley and Sons Inc
- Keywords
- catalyst recyling; Co leaching; oxetane carbonylation; β-hydrogen elimination; γ-butyrolactones
- Citation
- Bulletin of the Korean Chemical Society, v.44, no.12, pp 1049 - 1055
- Pages
- 7
- Journal Title
- Bulletin of the Korean Chemical Society
- Volume
- 44
- Number
- 12
- Start Page
- 1049
- End Page
- 1055
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70686
- DOI
- 10.1002/bkcs.12789
- ISSN
- 0253-2964
1229-5949
- Abstract
- γ-butyrolactones and their derivatives serve as the fundamental building blocks for a wide range of biologically significant and synthetically challenging natural products, which find extensive applications in various high-demand chemicals. In this study, we have successfully established a facile and atom-efficient synthesis of γ-butyrolactones through the carbonylative ring expansion of oxetanes. We employed both homogeneous and heterogenized bimetallic catalysts ([HCP-TPPM][Co(CO)4], where HCP refers to hyper cross-linked polymer and TPP denotes tetraphenylporphyrin, with M = Cr3+ and Al3+). While the homogeneous catalysts exhibited remarkable activity, the heterogeneous catalysts offered the distinct advantages of facilitating product separation and enabling catalyst recycling. Notably, during the catalyst recycling studies, we observed a decrease in catalytic activity attributed to cobaltate leaching. The hypothesis of cobaltate leaching through β-hydrogen elimination was validated by comparative studies using substrates with and without β-hydrogen in both batch and continuous flow catalytic processes. © 2023 Korean Chemical Society, Seoul & Wiley-VCH GmbH.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70686)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.