High- sensitivity C- reactive Protein Level is an Independent Predictor of Poor Prognosis in Cirrhotic Patients With Spontaneous Bacterial Peritonitis
DC Field | Value | Language |
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dc.contributor.author | Cho, Yuri | - |
dc.contributor.author | Park, So Youn | - |
dc.contributor.author | Lee, Jeong-Hoon | - |
dc.contributor.author | Lee, Dong Hyeon | - |
dc.contributor.author | Lee, Minjong | - |
dc.contributor.author | Yoo, Jeong-Ju | - |
dc.contributor.author | Choi, Won-Mook | - |
dc.contributor.author | Cho, Young Youn | - |
dc.contributor.author | Lee, Yun Bin | - |
dc.contributor.author | Yoon, Jae Woong | - |
dc.contributor.author | Kwon, Jung Hee | - |
dc.contributor.author | Cho, Eun Ju | - |
dc.contributor.author | Yu, Su Jong | - |
dc.contributor.author | Kim, Yoon Jun | - |
dc.contributor.author | Yoon, Jung-Hwan | - |
dc.contributor.author | Kim, Chung Yong | - |
dc.contributor.author | Lee, Hyo-Suk | - |
dc.date.accessioned | 2024-01-09T17:02:53Z | - |
dc.date.available | 2024-01-09T17:02:53Z | - |
dc.date.issued | 2014-05 | - |
dc.identifier.issn | 0192-0790 | - |
dc.identifier.issn | 1539-2031 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70844 | - |
dc.description.abstract | Background/Aims:The production of high-sensitivity C-reactive protein (hs-CRP) may be affected by hepatic function, and the clinical importance of hs-CRP in patients with liver cirrhosis is still not clear. The aim of this study was to evaluate the clinical implications of hs-CRP in cirrhotic patients with spontaneous bacterial peritonitis (SBP).Methods:We retrospectively investigated 336 consecutive patients treated for SBP from 2007 to 2012. The relationship between serum hs-CRP and the result of the treatment was assessed.Results:A response to antibiotics was observed in 182 patients (54.2%), and 126 patients (37.5%) died of SBP. The initial hs-CRP (odds ratio=1.061, P=0.016), coexistent hepatocellular carcinoma, and Child-Pugh (CP) score were independent prognostic factors for high in-hospital mortality. Serum hs-CRP level was also an independent predictor of lower antibiotic response rate (odds ratio=0.916, P<0.001). However, hs-CRP was negatively correlated with the CP score (r=-0.199, P<0.001) and Model for End-Stage Liver Disease score (r=-0.182, P=0.001).Conclusions:This study found that serum hs-CRP level is related to a lower response rate to antibiotics, a higher mortality rate in patients with SBP. The hs-CRP level was negatively correlated with the CP and Model for End-Stage Liver Disease scores, which suggests that the prognostic function of hs-CRP was not a surrogate for hepatic dysfunction. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | High- sensitivity C- reactive Protein Level is an Independent Predictor of Poor Prognosis in Cirrhotic Patients With Spontaneous Bacterial Peritonitis | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/MCG.0b013e3182a6cdef | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL GASTROENTEROLOGY, v.48, no.5, pp 444 - 449 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000334622300014 | - |
dc.identifier.scopusid | 2-s2.0-84898599205 | - |
dc.citation.endPage | 449 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 444 | - |
dc.citation.title | JOURNAL OF CLINICAL GASTROENTEROLOGY | - |
dc.citation.volume | 48 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | spontaneous bacterial peritonitis | - |
dc.subject.keywordAuthor | C-reactive protein | - |
dc.subject.keywordAuthor | liver cirrhosis | - |
dc.subject.keywordPlus | SYSTEMIC INFLAMMATORY RESPONSE | - |
dc.subject.keywordPlus | ACUTE-PHASE PROTEINS | - |
dc.subject.keywordPlus | AMYLOID-A PROTEIN | - |
dc.subject.keywordPlus | LIVER-DISEASE | - |
dc.subject.keywordPlus | MARKERS | - |
dc.subject.keywordPlus | DYSFUNCTION | - |
dc.subject.keywordPlus | OVERGROWTH | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | ENDOTOXIN | - |
dc.subject.keywordPlus | ASCITES | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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