Wound healing effect of visible light-curable chitosan with encapsulated EGF
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Shin-Hye | - |
dc.contributor.author | Kim, Eun-Hye | - |
dc.contributor.author | Lee, Hyung-Jae | - |
dc.contributor.author | Heo, Yun | - |
dc.contributor.author | Cho, Young-Min | - |
dc.contributor.author | Seo, Si-Yoong | - |
dc.contributor.author | Kim, Tae-Yeon | - |
dc.contributor.author | Suh, Hyeun-Woo | - |
dc.contributor.author | Kim, Mi-Kyung | - |
dc.contributor.author | Ito, Yoshihiro | - |
dc.contributor.author | Nah, Jae-Woon | - |
dc.contributor.author | Son, Tae-Il | - |
dc.date.available | 2019-03-08T13:36:23Z | - |
dc.date.issued | 2016-04 | - |
dc.identifier.issn | 1598-5032 | - |
dc.identifier.issn | 2092-7673 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/7107 | - |
dc.description.abstract | Low molecular O-carboxymethyl chitosan, a derivative of chitosan, was conjugated with a hydrophilic carboxymethyl group, following which the conjugate was modified with a furfuryl group. The chitosan derivative was cross-linked to encapsulate a model protein, bovine serum albumin (BSA), in the presence of Rose Bengal under visible light irradiation. The encapsulated BSA was slowly released from the matrix over 2 weeks. The modified chitosan exhibited antimicrobial activity and was non-cytotoxic to NIH3T3 fibroblasts. The wound healing effect of the cross-linked chitosan derivative was examined in Sprague-Dawley rats at 3, 7, and 14 days post-wounding. Cross-linked and murine epidermal growth factor (mEGF)-encapsulated chitosan derivatives healed wounds more rapidly in rats than non-encapsulated mEGF or chitosan derivative alone. Thus, visible light-curable chitosan has good potential for application as wound-healing matrix. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Wound healing effect of visible light-curable chitosan with encapsulated EGF | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s13233-016-4050-4 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR RESEARCH, v.24, no.4, pp 336 - 341 | - |
dc.identifier.kciid | ART002100930 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000374902700006 | - |
dc.identifier.scopusid | 2-s2.0-84964462198 | - |
dc.citation.endPage | 341 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 336 | - |
dc.citation.title | MACROMOLECULAR RESEARCH | - |
dc.citation.volume | 24 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | chitosan | - |
dc.subject.keywordAuthor | wound healing | - |
dc.subject.keywordAuthor | protein encapsulation | - |
dc.subject.keywordAuthor | epidermal growth factor | - |
dc.subject.keywordAuthor | visible light-curable | - |
dc.subject.keywordPlus | BIOMEDICAL APPLICATIONS SYNTHESIS | - |
dc.subject.keywordPlus | MOLECULAR-WEIGHT CHITOSAN | - |
dc.subject.keywordPlus | IN-VITRO BIOCOMPATIBILITY | - |
dc.subject.keywordPlus | CARBOXYMETHYL CHITOSAN | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | ANTIBACTERIAL ACTIVITY | - |
dc.subject.keywordPlus | ANTIADHESION AGENT | - |
dc.subject.keywordPlus | TITANIUM PLATE | - |
dc.subject.keywordPlus | FISH GELATIN | - |
dc.subject.keywordPlus | DRESSINGS | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.