The Presence of Periodic Limb Movement Disorder in a Patient with Diabetes Mellitus and Optic Atrophy (Wolfram Syndrome)
- Authors
- Kwon, B.S.; Han, S.-H.; Lee, S.-A.
- Issue Date
- 2014
- Publisher
- Korean Society of Sleep Medicine
- Keywords
- Periodic limb movement disorder; Wolfram syndrome; Diabetic autonomic neuropathy
- Citation
- Sleep Medicine Research, v.5, no.2, pp 67 - 71
- Pages
- 5
- Journal Title
- Sleep Medicine Research
- Volume
- 5
- Number
- 2
- Start Page
- 67
- End Page
- 71
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71573
- DOI
- 10.17241/smr.2014.5.2.67
- ISSN
- 2093-9175
2233-8853
- Abstract
- Wolfram syndrome (WFS) is characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD), together known as DIDMOAD. This syndrome is a rare autosomal recessive neurodegenerative disorder and typically begins wtih insulin-dependent diabetes mellitus. Periodic limb movement disorder (PLMD) is characterized by periodic episodes of repetitive, highly stereotyped, limb movement during sleep, which results in disturbed sleep. Its pathophysiology is unclear. It is associated with many conditions, but we were unable to find a previous report regarding WFS accompanied by PLMD. We therefore report, for the first time, about a patient with WFS presenting with PLMD and discuss its pathomechanism with a literature review.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71573)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.