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Will ET<sub>A</sub>-antibody arouse new interest in cancer therapeutics?
- Authors
- Park, Ji-Young; Lee, Chang-Han
- Issue Date
- May-2022
- Publisher
- CELL PRESS
- Keywords
- cancer stem cell; ETA antagonist; GPCR; therapeutic antibody
- Citation
- TRENDS IN PHARMACOLOGICAL SCIENCES, v.43, no.5, pp 352 - 354
- Pages
- 3
- Journal Title
- TRENDS IN PHARMACOLOGICAL SCIENCES
- Volume
- 43
- Number
- 5
- Start Page
- 352
- End Page
- 354
- ISSN
- 0165-6147
1873-3735
- Abstract
- Although endothelin receptor type A (ETA) is emerging as a novel anticancer target, previously only small molecule drugs have been available as ETA antagonists. Ju and colleagues have successfully developed a functional anti-ETA antibody for colorectal cancer.
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