Small intestinal adenocarcinoma accompanied by lynch syndrome: A case report
DC Field | Value | Language |
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dc.contributor.author | Yoon, Kyoung Won | - |
dc.contributor.author | Jo, Jaemin | - |
dc.contributor.author | Lee, Donghyoun | - |
dc.date.accessioned | 2024-04-29T09:01:16Z | - |
dc.date.available | 2024-04-29T09:01:16Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.issn | 1536-5964 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73545 | - |
dc.description.abstract | RATIONALE: Lynch syndrome is caused by germline mutations of DNA mismatch repair genes. A significant risk increase for several types of cancer is one of the characteristics of lynch syndrome. PATIENT CONCERNS: A 45-year-old female presented to the emergency department with abdominal pain that had persisted for a month. DIAGNOSES: The abdominal and pelvic computed tomography scan showed edematous and thickening of the proximal small bowel wall, as well as dilatation of the proximal bowel and stomach. INTERVENTIONS: Tumor resection of the small bowel was performed, and adenocarcinoma was confirmed pathologically. Microsatellite instability was also confirmed. OUTCOMES: Postoperative imaging revealed soft tissue lesions with potential for tumor seeding. Two months after the first surgery, a secondary surgery was performed as a result of cancer recurrence. The patient received chemotherapy with capecitabine. The latest computed tomography scan, performed 19 months after the cessation of chemotherapy, did not show any recurrence. LESSONS: In the rare incidence of small bowel cancer genetic mutation testing and detailed family history should be actively considered. Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NLM (Medline) | - |
dc.title | Small intestinal adenocarcinoma accompanied by lynch syndrome: A case report | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/MD.0000000000035323 | - |
dc.identifier.bibliographicCitation | Medicine, v.102, no.39 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 001077900900001 | - |
dc.identifier.scopusid | 2-s2.0-85172828991 | - |
dc.citation.number | 39 | - |
dc.citation.title | Medicine | - |
dc.citation.volume | 102 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | case report | - |
dc.subject.keywordAuthor | lynch syndrome | - |
dc.subject.keywordAuthor | microsatellite instability | - |
dc.subject.keywordAuthor | small intestinal cancer | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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