Small intestinal adenocarcinoma accompanied by lynch syndrome: A case reportopen access
- Authors
- Yoon, Kyoung Won; Jo, Jaemin; Lee, Donghyoun
- Issue Date
- Sep-2023
- Publisher
- NLM (Medline)
- Keywords
- case report; lynch syndrome; microsatellite instability; small intestinal cancer
- Citation
- Medicine, v.102, no.39
- Journal Title
- Medicine
- Volume
- 102
- Number
- 39
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73545
- DOI
- 10.1097/MD.0000000000035323
- ISSN
- 0025-7974
1536-5964
- Abstract
- RATIONALE: Lynch syndrome is caused by germline mutations of DNA mismatch repair genes. A significant risk increase for several types of cancer is one of the characteristics of lynch syndrome. PATIENT CONCERNS: A 45-year-old female presented to the emergency department with abdominal pain that had persisted for a month. DIAGNOSES: The abdominal and pelvic computed tomography scan showed edematous and thickening of the proximal small bowel wall, as well as dilatation of the proximal bowel and stomach. INTERVENTIONS: Tumor resection of the small bowel was performed, and adenocarcinoma was confirmed pathologically. Microsatellite instability was also confirmed. OUTCOMES: Postoperative imaging revealed soft tissue lesions with potential for tumor seeding. Two months after the first surgery, a secondary surgery was performed as a result of cancer recurrence. The patient received chemotherapy with capecitabine. The latest computed tomography scan, performed 19 months after the cessation of chemotherapy, did not show any recurrence. LESSONS: In the rare incidence of small bowel cancer genetic mutation testing and detailed family history should be actively considered. Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.
- Files in This Item
-
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73545)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.