Microfluidics for disease diagnostics based on surface-enhanced raman scattering detectionopen access
- Authors
- Yu, Xiangdong; Park, Sohyun; Lee, Sungwoon; Joo, Sang-Woo; Choo, Jaebum
- Issue Date
- Apr-2024
- Publisher
- Korea Nano Technology Research Society
- Keywords
- Biomedical diagnostics; Lab-on-a-chip; Microfluidics; On-chip detection; Surface-enhanced Raman scattering
- Citation
- Nano convergence, v.11, no.1
- Journal Title
- Nano convergence
- Volume
- 11
- Number
- 1
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73803
- DOI
- 10.1186/s40580-024-00424-7
- ISSN
- 2196-5404
2196-5404
- Abstract
- This review reports diverse microfluidic systems utilizing surface-enhanced Raman scattering (SERS) detection for disease diagnosis. Integrating SERS detection technology, providing high-sensitivity detection, and microfluidic technology for manipulating small liquid samples in microdevices has expanded the analytical capabilities previously confined to larger settings. This study explores the principles and uses of various SERS-based microfluidic devices developed over the last two decades. Specifically, we investigate the operational principles of documented SERS-based microfluidic devices, including continuous-flow channels, microarray-embedded microfluidic channels, droplet microfluidic channels, digital droplet channels, and gradient microfluidic channels. We also examine their applications in biomedical diagnostics. In conclusion, we summarize the areas requiring further development to translate these SERS-based microfluidic technologies into practical applications in clinical diagnostics. © 2024. The Author(s).
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- Appears in
Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
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