Positive Results from the Fecal Immunochemical Test Can Be Related to Dementia: A Nationwide Population-Based Study in South Korea
DC Field | Value | Language |
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dc.contributor.author | Jun, Y.K. | - |
dc.contributor.author | Lee, S.W. | - |
dc.contributor.author | Kim, K.W. | - |
dc.contributor.author | Moon, J.M. | - |
dc.contributor.author | Koh, S.-J. | - |
dc.contributor.author | Lee, H.J. | - |
dc.contributor.author | Kim, J.S. | - |
dc.contributor.author | Han, K. | - |
dc.contributor.author | Im, J.P. | - |
dc.date.accessioned | 2024-05-28T02:30:31Z | - |
dc.date.available | 2024-05-28T02:30:31Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 1387-2877 | - |
dc.identifier.issn | 1875-8908 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73918 | - |
dc.description.abstract | BACKGROUND: The fecal immunochemical test (FIT) is widely used in screening for colorectal cancer (CRC), but FIT results can be positive for diseases other than CRC. OBJECTIVE: We investigated the association between positive results of FIT and the incidence of dementia using a nationwide database. METHODS: FIT-positive participants were collected from a database provided by the Korean National Health Insurance Service. RESULTS: The incidence of all kinds of dementia was higher in FIT-positive than FIT-negative subjects (p < 0.0001). FIT-positive participants had a higher risk of Alzheimer's disease (AD) (p < 0.0001) and vascular dementia (p = 0.0002), compared to participants with FIT negativity. The risk of all kinds of dementia or AD in FIT-positive participants was higher in younger (age < 65 years) than older participants (p < 0.0001 for all kinds of dementia; p = 0.0002 for AD). CONCLUSION: FIT positivity was correlated with an increased risk of dementia, especially in participants under 65 years of age. The study suggests that clinicians can consider dementia when FIT-positive participants fail to show any malignancies. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NLM (Medline) | - |
dc.title | Positive Results from the Fecal Immunochemical Test Can Be Related to Dementia: A Nationwide Population-Based Study in South Korea | - |
dc.type | Article | - |
dc.identifier.doi | 10.3233/JAD-220770 | - |
dc.identifier.bibliographicCitation | Journal of Alzheimer's disease : JAD, v.91, no.4, pp 1515 - 1525 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000939222800025 | - |
dc.identifier.scopusid | 2-s2.0-85148679183 | - |
dc.citation.endPage | 1525 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1515 | - |
dc.citation.title | Journal of Alzheimer's disease : JAD | - |
dc.citation.volume | 91 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | Alzheimer’s disease | - |
dc.subject.keywordAuthor | dementia | - |
dc.subject.keywordAuthor | occult blood | - |
dc.subject.keywordAuthor | population surveillance | - |
dc.subject.keywordAuthor | vascular dementia | - |
dc.subject.keywordPlus | EARLY-ONSET DEMENTIA | - |
dc.subject.keywordPlus | OCCULT BLOOD-TEST | - |
dc.subject.keywordPlus | ULCERATIVE-COLITIS | - |
dc.subject.keywordPlus | GUT MICROBIOTA | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | PERFORMANCE | - |
dc.subject.keywordPlus | HEMOGLOBIN | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | CALPROTECTIN | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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