Possible therapeutic effect of orally administered ribavirin for respiratory syncytial virus-induced acute respiratory distress syndrome in an immunocompetent patient: A case reportopen access
- Authors
- Yoon, Byung Woo; Lee, Seung Hyeun
- Issue Date
- Dec-2017
- Publisher
- BioMed Central Ltd.
- Keywords
- Acute respiratory distress syndrome; Case report; Respiratory syncytial virus; Ribavirin
- Citation
- Journal of Medical Case Reports, v.11, no.1
- Journal Title
- Journal of Medical Case Reports
- Volume
- 11
- Number
- 1
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73989
- DOI
- 10.1186/s13256-017-1514-x
- ISSN
- 1752-1947
- Abstract
- Background: Human respiratory syncytial virus usually causes self-limiting upper respiratory infection and occasionally causes pneumonia in immunocompromised hosts. Respiratory syncytial virus-induced severe pneumonia or acute respiratory distress syndrome in immunocompetent adults has been rarely described. Unfortunately, optimal treatment has not been established for this potentially fatal condition. We report a case of respiratory syncytial virus-induced acute respiratory distress syndrome occurring in a previously healthy man successfully treated with orally administered ribavirin. Case presentation: An 81-year-old previously healthy Korean man presented with cough, dyspnea, and febrile sensation. He had hypoxemia with diffuse ground glass opacity evident on chest radiography, which progressed and required mechanical ventilation. All microbiological tests were negative except multiplex real-time reverse transcriptase polymerase chain reaction using respiratory specimen, which was positive for human adenovirus. Under the diagnosis of respiratory syncytial virus-induced acute respiratory distress syndrome, orally administered ribavirin was administered and he recuperated completely without complications. Conclusion: This case demonstrates the potential usefulness of orally administered ribavirin as a therapeutic option for severe respiratory syncytial virus infection, at least in an immunocompetent host. © 2017 The Author(s).
- Files in This Item
-
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73989)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.