Incidence of ionized hypomagnesemia in adult patients undergoing non-cardiac major surgery: a prospective observational trial
- Authors
- Shin, Hyun-Jung; Han, Jiwon; Yim, Subin; Do, Sang-Hwan
- Issue Date
- Jan-2022
- Publisher
- JOHN LIBBEY EUROTEXT LTD
- Keywords
- ionized magnesium; total magnesium; hypomagnesemia
- Citation
- MAGNESIUM RESEARCH, v.35, no.1, pp 11 - 17
- Pages
- 7
- Journal Title
- MAGNESIUM RESEARCH
- Volume
- 35
- Number
- 1
- Start Page
- 11
- End Page
- 17
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74429
- DOI
- 10.1684/mrh.2022.0498
- ISSN
- 0953-1424
1952-4021
- Abstract
- Background: The present study aimed to investigate the incidence of preoperative ionized hypomagnesemia and compare with that of total hypomagnesemia. Methods: This prospective observational study included 536 patients aged >20 years who were scheduled for elective surgery. Total and ionized magnesium levels were evaluated before and after the surgery. Based on these levels, patients were classified into the following groups: ionized hypo(<0.42 mmol/L), normo- (0.42-0.59 mmol/L) and hypermagnesemia (>0.59 mmol/ L), as well as total hypo- (<1.9 mg/dL [0.78 mmol/L]), normo- (1.9-2.7 mg/dL [0.781.11 mmol/L]) and hypermagnesemia (>2.7 mg/dL [1.11 mmol/L]). The primary objective was to establish the incidence of preoperative ionized hypomagnesemia. Results: There was a marked difference between the incidence of preoperative ionized and total hypomagnesemia (28% vs. 19%; p<0.001). The postoperative values of ionized magnesium, ionized calcium, and albumin were significantly lower than the respective preoperative values (p<0.001 for all three variables). Conclusion: The incidence of hypomagnesemia, determined by ionized magnesium concentration, was higher than that determined by total magnesium concentration.
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