桂枝茯苓丸의 配伍분석과 그 생리활성Analysis for Compatibility of Gyejibongnyeong-hwan and Its Biological Activities
- Authors
- 김도회; 정양삼; 윤미정; 윤유식; 신순식
- Issue Date
- Nov-2016
- Publisher
- 대한한의학방제학회
- Keywords
- Gyejibongnyeong-hwan; system of chief; deputy; assistant; and envoy; biological activity; cellular level; animal level; human level
- Citation
- 대한한의학 방제학회지, v.24, no.4, pp 353 - 365
- Pages
- 13
- Journal Title
- 대한한의학 방제학회지
- Volume
- 24
- Number
- 4
- Start Page
- 353
- End Page
- 365
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/7807
- DOI
- 10.14374/HFS.2016.24.4.353
- ISSN
- 2288-5641
2288-5641
- Abstract
- Objectives : We analysed Gyejibongnyeong-hwan’s compatibility principle and investigated biological activities by categorizing with molecular level, cellular level, animal level and human level based on Korean study for this formula.
Methods : Gyejibongnyeong-hwan’s compatibiltity principle was examined by the system of chief, deputy, assistant,and envoy. We looked into studies that presented in Korea from 1956 to 2016 about Gyejibongnyeong-hwan through Korea Institute of Oriental Medicine, Korean medicine information system (OASIS). Then classify into molecular level, cellular level, animal level and human level to analyse.
Results : According to the system of chief, deputy, assistant, and envoy, chief herb is Cinnamomi Ramulus, deputy herb is Persicae Semen, assistant herb is Moutan Cortex, Paeoniae Radix, Poria, and envoy herb is Mel. Biological activities can be detected in transcription factors, enzymes, and inflammatory mediators for molecular level. For cellular level, it can be determined in human uterine endometrial cancer cell, human hepatocarcinoma cell, and human platelets. In mouse and rats for animal level, in overian cystoma, menorrhalgia, quality of life improvement in postmenopausal women, and blood stasis with motor vehicle accident for human level, biological activities was caught.
Conclusions : From above results, Gyejibongnyeong-hwan is composed in line with the system of chief, deputy, assistan, and envoy. Biological activities are effective to improvement of menorrhalgia, anti-cancer, anti-oxidative,anti-inflammation, improvement of atherosclerosis, analgesic, anti-convulsion, wound healing, and improvement of liver function.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > College of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/7807)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.