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Anticancer Activities of Medicinal Plants: Modulation of p53 Expression and Induction of Apoptosis

Authors
Parveen, AmnaAkash, Muhammad Sajid HamidRehman, KanwalWhang, Wan Kyunn
Issue Date
2016
Publisher
BEGELL HOUSE INC
Keywords
Anticancer properties; apoptosis induction; expression of p53; medicinal plants
Citation
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION, v.26, no.3, pp 257 - 271
Pages
15
Journal Title
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
Volume
26
Number
3
Start Page
257
End Page
271
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/8749
DOI
10.1615/CritRevEukaryotGeneExpr.2016016683
ISSN
1045-4403
2162-6502
Abstract
For the treatment of several types of cancers, tumors and malignancies, scientists are investigating natural sources to discover novel therapeutic agents from medicinal plants having diverse anticancer properties. Research on natural products is being conducted to identify unexplored phytochemical constituents that have been proven to have diverse pharmacological activities. Several medicinal plants have been reported to regulate the progression of different types of cancers, tumors, and malignancies. In this article, we briefly summarize the recent progress in exploring the anticancer properties of various medicinal plants reported to modulate the expression of p53 and the induction of apoptosis. These plants provide a rich source of chemo-protective agents that can ultimately be used to manage cancer progression.
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