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Novel Dammarane-Type Triterpene Saponins from Panax ginseng Root
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Dong Gu | - |
| dc.contributor.author | Lee, Ah Young | - |
| dc.contributor.author | Kim, Kyung-Tack | - |
| dc.contributor.author | Cho, Eun Ju | - |
| dc.contributor.author | Lee, Sang Hyun | - |
| dc.date.available | 2019-03-08T16:37:35Z | - |
| dc.date.issued | 2015-11 | - |
| dc.identifier.issn | 0009-2363 | - |
| dc.identifier.issn | 1347-5223 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/8953 | - |
| dc.description.abstract | Four phytochemical constituents were isolated from Panax ginseng root by repeated column chromatography (CC), medium pressure liquid chromatography (MPLC), high-speed counter current chromatography (HSCCC), and semi-preparative HPLC. Their structures were elucidated as the dammarane-type triterpene saponins ginsenoside-Rg18 (1), 6-acetyl ginsenoside-Rg3 (2), ginsenoside-Rs11 (3), and ginsenoside-Re7 (4) based on spectral data. Compounds 1-4 from P. ginseng root were new compounds from nature. They showed good hydroxyl radical scavenging activity and anti-bacterial activity against Escherichia coli and Staphylococcus aureus. However, they did not show any anti-inflammatory activity. In addition, they inhibited the growth of adenocarcinoma gastric stomach cells. Among them, ginsenoside-Rs11 (3) showed the best anti-oxidative, anti-bacterial, and anti-cancer activities. | - |
| dc.format.extent | 8 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | PHARMACEUTICAL SOC JAPAN | - |
| dc.title | Novel Dammarane-Type Triterpene Saponins from Panax ginseng Root | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1248/cpb.c15-00302 | - |
| dc.identifier.bibliographicCitation | CHEMICAL & PHARMACEUTICAL BULLETIN, v.63, no.11, pp 927 - 934 | - |
| dc.description.isOpenAccess | N | - |
| dc.identifier.wosid | 000363908300011 | - |
| dc.identifier.scopusid | 2-s2.0-84955448036 | - |
| dc.citation.endPage | 934 | - |
| dc.citation.number | 11 | - |
| dc.citation.startPage | 927 | - |
| dc.citation.title | CHEMICAL & PHARMACEUTICAL BULLETIN | - |
| dc.citation.volume | 63 | - |
| dc.type.docType | Article | - |
| dc.publisher.location | 일본 | - |
| dc.subject.keywordAuthor | Panax ginseng | - |
| dc.subject.keywordAuthor | white ginseng | - |
| dc.subject.keywordAuthor | dammarane | - |
| dc.subject.keywordAuthor | ginsenoside-Rs11 | - |
| dc.subject.keywordAuthor | adenocarcinoma gastric stomach | - |
| dc.subject.keywordPlus | GINSENOSIDES | - |
| dc.subject.keywordPlus | QUINQUEFOLIUM | - |
| dc.subject.keywordPlus | CONSTITUENTS | - |
| dc.subject.keywordPlus | GLYCOSIDES | - |
| dc.subject.keywordPlus | LEAVES | - |
| dc.subject.keywordPlus | ELSD | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
| dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
| dc.description.journalRegisteredClass | sci | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
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