Detailed Information
Cited 7 time in 
Cited 12 time in 
Cited 12 time in
Metadata Downloads
Novel Dammarane-Type Triterpene Saponins from Panax ginseng Root
- Issue Date
- Nov-2015
- Publisher
- PHARMACEUTICAL SOC JAPAN
- Keywords
- Panax ginseng; white ginseng; dammarane; ginsenoside-Rs11; adenocarcinoma gastric stomach
- Citation
- CHEMICAL & PHARMACEUTICAL BULLETIN, v.63, no.11, pp 927 - 934
- Pages
- 8
- Journal Title
- CHEMICAL & PHARMACEUTICAL BULLETIN
- Volume
- 63
- Number
- 11
- Start Page
- 927
- End Page
- 934
- ISSN
- 0009-2363
1347-5223
- Abstract
- Four phytochemical constituents were isolated from Panax ginseng root by repeated column chromatography (CC), medium pressure liquid chromatography (MPLC), high-speed counter current chromatography (HSCCC), and semi-preparative HPLC. Their structures were elucidated as the dammarane-type triterpene saponins ginsenoside-Rg18 (1), 6-acetyl ginsenoside-Rg3 (2), ginsenoside-Rs11 (3), and ginsenoside-Re7 (4) based on spectral data. Compounds 1-4 from P. ginseng root were new compounds from nature. They showed good hydroxyl radical scavenging activity and anti-bacterial activity against Escherichia coli and Staphylococcus aureus. However, they did not show any anti-inflammatory activity. In addition, they inhibited the growth of adenocarcinoma gastric stomach cells. Among them, ginsenoside-Rs11 (3) showed the best anti-oxidative, anti-bacterial, and anti-cancer activities.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Biotechnology & Natural Resource > ETC > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.