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Regulation of Escherichia coli RNase III activityopen access
- Authors
- Lim, Boram; Sim, Minji; Lee, Howoon; Hyun, Seogang; Lee, Younghoon; Hahn, Yoonsoo; Shin, Eunkyoung; Lee, Kangseok
- Issue Date
- Aug-2015
- Publisher
- MICROBIOLOGICAL SOCIETY KOREA
- Keywords
- RNase III; mRNA stability; regulator; catalytic mechanism; stress response; osmotic stress
- Citation
- JOURNAL OF MICROBIOLOGY, v.53, no.8, pp 487 - 494
- Pages
- 8
- Journal Title
- JOURNAL OF MICROBIOLOGY
- Volume
- 53
- Number
- 8
- Start Page
- 487
- End Page
- 494
- ISSN
- 1225-8873
1976-3794
- Abstract
- Bacterial cells respond to changes in the environment by adjusting their physiological reactions. In cascades of cellular responses to stresses of various origins, rapid modulation of RNA function is known to be an effective biochemical adaptation. Among many factors affecting RNA function, RNase III, a member of the phylogenetically highly conserved endoribonuclease III family, plays a key role in posttranscriptional regulatory pathways in Escherichia coli. In this review, we provide an overview of the factors affecting RNase III activity in E. coli.
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