Seven-Day Continuous Abstinence Rate from Smoking at 1, 2, or 3 Years after the Use of Vareniclineopen access
- Authors
- Kim, Jin Se; Jang, Ju Young; Park, Eun Hye; Lee, Joo Young; Gu, Kang Mo; Jung, Jae Woo; Choi, Jae Chol; Shin, Jong Wook; Park, In Won; Choi, Byoung Whui; Kim, Jae Yeol
- Issue Date
- Apr-2015
- Publisher
- TAEHAN KYORHAEK HYOPHOE-KOREAN ACAD TUBERCULOSIS & RESPIRATORY DISEASES
- Keywords
- Compliance; Smoking; Varenicline
- Citation
- TUBERCULOSIS AND RESPIRATORY DISEASES, v.78, no.2, pp 92 - 98
- Pages
- 7
- Journal Title
- TUBERCULOSIS AND RESPIRATORY DISEASES
- Volume
- 78
- Number
- 2
- Start Page
- 92
- End Page
- 98
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/9667
- DOI
- 10.4046/trd.2015.78.2.92
- ISSN
- 1738-3536
2005-6184
- Abstract
- Background: Varenicline, a selective partial agonist/ antagonist of the alpha 4 beta 2 nicotinic receptor, has proven effectiveness for smoking cessation by several randomized, controlled trials. Because few studies have evaluated the long-term efficacy of varenicline, we tried to evaluate the smoking status of varenicline users up to 3 years after the initial prescription of the drug. Methods: We interviewed varenicline users who were prescribed the drug from June 2007 to May 2010 by telephone, from June 2010 to May 2011. Results: One- hundred and thirty- three of 250 varenicline users (53.2%) were available for the survey. Seven-day continuous abstinence from smoking was adhered to by 17 of 39 respondents (43.6%) at 1 year, and 11 of 36 (30.6%) and 19 of 58 (32.8%) at 2 and 3 years since the first use of varenicline, respectively. Compared to current smokers, successful quitters were older (55.0 years vs. 49.9 years, p=0.01), had better compliance to the 12-week course (27.7 vs. 9.3%, p=0.01), and had taken varenicline longer (10.1 vs. 5.9 weeks, p=0.01). Fifty- four of 71 current smokers (76.1%) were willing to stop smoking in the near future. The preferred ways to cease smoking were will-power (48.1%), varenicline (25.9%), nicotine replacement therapy (11.1%), and others (14.9%). Conclusion: Smokers should be encouraged to stick to the proven way for recommended period of time for successful cessation of smoking.
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