Effects of dietary selenium on host response to necrotic enteritis in young broilers
- Authors
- Xu, Shouzhen; Lee, Sung-Hyen; Lillehoj, Hyun S.; Hong, Yeong Ho; Bravo, David
- Issue Date
- Feb-2015
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Selenium; Chicken; Necrotic enteritis; Cytokine; beta-defensin
- Citation
- RESEARCH IN VETERINARY SCIENCE, v.98, pp 66 - 73
- Pages
- 8
- Journal Title
- RESEARCH IN VETERINARY SCIENCE
- Volume
- 98
- Start Page
- 66
- End Page
- 73
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/9923
- DOI
- 10.1016/j.rvsc.2014.12.004
- ISSN
- 0034-5288
1532-2661
- Abstract
- The effects of dietary supplementation of young broiler chickens with an organic selenium (Se) formulation, B-Traxim Se, on experimental necrotic enteritis (NE) were studied. Chickens treated with three Se doses (0.25, 0.50, 1.00 mg/kg) from hatch were orally challenged with Eimeria maxima at 14 days of age followed by Clostridium perfringens to induce NE. Chickens fed with 0.50 mg/kg Se showed significantly increased body weights and antibody levels against NetB, and significantly reduced gut lesions compared with non-supplemented chickens. However, there were no significant differences in Eimeria oocyst shedding between the Se-treated and non-supplemented groups. Levels of IL-1 beta, IL-6, IL-8, iNOS, LITAF, TNFSF15, AvBD6, AvBD8, and AvBD13 transcripts were increased in the gut and spleen of at least one of the three Se-treated groups compared with the non-treated group. These results suggest that dietary supplementation of young broilers with Se might be beneficial to reduce the negative consequence of NE. (C) 2014 Published by Elsevier Ltd.
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