Motion characterization scheme to minimize motion artifacts in intravital microscopy
- Authors
- Lee, Sungon; Courties, Gabriel; Nahrendorf, Matthias; Weissleder, Ralph; Vinegoni, Claudio
- Issue Date
- Mar-2017
- Publisher
- SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
- Keywords
- motion artifact; intravital microscopy; motion compensation; in vivo imaging
- Citation
- JOURNAL OF BIOMEDICAL OPTICS, v.22, no.3, pp.1 - 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF BIOMEDICAL OPTICS
- Volume
- 22
- Number
- 3
- Start Page
- 1
- End Page
- 8
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/10120
- DOI
- 10.1117/1.JBO.22.3.036005
- ISSN
- 1083-3668
- Abstract
- Respiratory- and cardiac-induced motion artifacts pose a major challenge for in vivo optical imaging, limiting the temporal and spatial imaging resolution in fluorescence laser scanning microscopy. Here, we present an imaging platform developed for in vivo characterization of physiologically induced axial motion. The motion characterization system can be straightforwardly implemented on any conventional laser scanning microscope and can be used to evaluate the effectiveness of different motion stabilization schemes. This method is particularly useful to improve the design of novel tissue stabilizers and to facilitate stabilizer positioning in real time, therefore facilitating optimal tissue immobilization and minimizing motion induced artifacts. (C) 2017 Society of Photo-Optical Instrumentation Engineers (SPIE).
- Files in This Item
-
Go to Link
- Appears in
Collections - COLLEGE OF ENGINEERING SCIENCES > DEPARTMENT OF ROBOT ENGINEERING > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.