Chromofluorogenic naphthoquinolinedione-based probes for sensitive detection and removal of Hg2+ in aqueous solutions
DC Field | Value | Language |
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dc.contributor.author | Kumar, Ashwani | - |
dc.contributor.author | Hur, Won | - |
dc.contributor.author | Seong, Gi Hun | - |
dc.contributor.author | Kumar, Subodh | - |
dc.contributor.author | Chae, Pil Seok | - |
dc.date.accessioned | 2022-07-18T01:19:25Z | - |
dc.date.available | 2022-07-18T01:19:25Z | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 0143-7208 | - |
dc.identifier.issn | 1873-3743 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/107960 | - |
dc.description.abstract | Y Mercury ions are an industrial and environmental toxin that need to be monitored and regulated in aqueous samples. We prepared six probes (1-6) using a naphthoquinolinedione ring as a fluorophore platform that contains different substituents on the quinolone ring. All probes showed abilities to selectively bind Hg2+, but their sensitivity to the detection of this metal ion significantly varied depending on the substituent pattern. Among these probes, probe 5 with Br and CN substituents on the quinolone ring was most effective for the sensitive detection of Hg2+ in aqueous solutions. This probe showed a naked-eye color change from yellow to purple upon binding to Hg2+. A ratio-metric method using UV-visible absorption data gave a limit of detection (LOD) of 20 nM, while the fluorescence-based result yielded an LOD of 0.047 pM. When bio-samples such as human urine and serum were used as media, the fluorescence-based LOD of this probe for Hg2+ detection increased to 50 nM. Probe 5 was also effective at detecting methylmercury, an organic mercury species, dissolved in drainage water or urine. Based on the results of DLS, FE-SEM, and DFT calculations, the probe appeared to form large aggregates and undergo photo-induced electron transfer (PET) upon Hg2+ binding, both of which are responsible for the probe fluorescence quenching. Probe 5 also showed the ability to sense Hg2+ within three different types of human cells: Brain cells (U87MG), Hela cells and skin cancer cells (SK-MEL28). Furthermore, this probe holds significant potential for on-site applications since various solid supports such as silica gel, filter papers and TLC plates were effectively used for sensitive and selective Hg2+ sensing, following probe coating/adsorption. | - |
dc.format.extent | 13 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier BV | - |
dc.title | Chromofluorogenic naphthoquinolinedione-based probes for sensitive detection and removal of Hg2+ in aqueous solutions | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1016/j.dyepig.2021.110025 | - |
dc.identifier.scopusid | 2-s2.0-85121253158 | - |
dc.identifier.wosid | 000743263900002 | - |
dc.identifier.bibliographicCitation | Dyes and Pigments, v.198, pp 1 - 13 | - |
dc.citation.title | Dyes and Pigments | - |
dc.citation.volume | 198 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 13 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Textiles | - |
dc.subject.keywordPlus | SELECTIVE DUAL DETECTION | - |
dc.subject.keywordPlus | FLUORESCENT CHEMOSENSORS | - |
dc.subject.keywordPlus | CASCADE DETECTION | - |
dc.subject.keywordPlus | METAL-IONS | - |
dc.subject.keywordPlus | MERCURY | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | METHYLMERCURY | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | PYRENESULFONAMIDE | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordAuthor | Naphthoquinolinedione | - |
dc.subject.keywordAuthor | Hg2+/methylmercury detection | - |
dc.subject.keywordAuthor | Fluorescence quenching | - |
dc.subject.keywordAuthor | Naked eye detection | - |
dc.subject.keywordAuthor | Bio-detection | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0143720821008913?via%3Dihub | - |
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