Two-dimensional packing patterns of amino acid surfactant and higher alcohols in an aqueous phase and their associated packing parameters
- Authors
- Seo, Dong-Sung; Kim, Jin-Chul; Sohn, Hong-Ha; Cho, Wan-Goo; Lee, Sang Uck; Kim, Eun-Young; Tae, Giyoong; Kim, Jong Dai; Lee, Shin Young; Lee, Hyeon Yong
- Issue Date
- May-2004
- Publisher
- Academic Press
- Keywords
- Amino acid surfactant; Bilayer; Higher alcohols; Molecular dynamics; Packing parameter
- Citation
- Journal of Colloid and Interface Science, v.273, no.2, pp 596 - 603
- Pages
- 8
- Indexed
- SCIE
SCOPUS
- Journal Title
- Journal of Colloid and Interface Science
- Volume
- 273
- Number
- 2
- Start Page
- 596
- End Page
- 603
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/110314
- DOI
- 10.1016/j.jcis.2004.01.004
- ISSN
- 0021-9797
1095-7103
- Abstract
- An amino acid surfactant, monosodium N-stearoyl-L-glutamate (MSSG), was assumed to associate with higher alcohols (HAs) in 1:1 molar ratio in an aqueous phase, and the packing parameters of the 1/1 MSSG/HA associates, Pa, were calculated by molecular dynamics (MD). Pa is defined as A t1(lt1+lt2)/ahlt1, where At1 stands for the cross-sectional area of the MSSG tail, l t1 for the length of the MSSG tail, lt2 for the length of the HA tail, and ah for the area of the MSSG head group. The P a value increased from 0.83 to 1.02 as the HA tail length (l t2) increased from C14 to C22. Associates of HAs having longer tails with MSSG are likely to fit better into bilayers because Pa is closer to 1 when lt2 is longer. In the graphical results of the MD simulation for the association, however, a steric hindrance was found between the head groups of MSSG/HA when lt2 was ≥C 19. Based on this result, HA was classified into short-chain HA (SCHA, lt2< C19) and long-chain HA (LCHA, l t2≥C19), and several possible packing units, composed of compositional combinations of MSSG, SCHA, and LCHA, were proposed. The packing unit is a building block which could constitute bilayers, and it is composed of variable compositional combinations of MSSG/HA. Assuming that SCHA associates with MSSG, the packing parameter, Punit, was calculated in a water box by MD for each packing unit. Punit is the packing parameter of a packing unit and it is defined as Vu/l uau, where Vu is the tail volume of the packing unit, lu is the chain length, and au is the head area. For the calculation, stearyl alcohol (C18-OH, SA) was chosen as a SCHA and behenyl alcohol (C22-OH, BA) as a LCHA. When the compositional ratio MSSG:SCHA:LCHA was 1:1:1, Punit was around 1. The packing unit having Punit of around 1 formed a colloidally stable suspension for 30 days and its aggregate was a lamellar structure. However, the other packing units, for which Punit deviates significantly from 1, precipitated out in their suspensions and showed no evidence of a lamellar structure. According to the graphical MD simulations for the compositional MSSG/SCHA/LCHA associations in bilayers, vertical steric hindrance was found between LCHAs when Punit deviated significantly from 1. The steric hindrance would prevent the packing units from forming a stable bilayer and induce precipitation in the suspensions. Therefore, a proper combinational ratio of MSSG:LCHA:SCHA would play a major role in forming a lamellar structure.
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Collections - COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY > DEPARTMENT OF CHEMICAL AND MOLECULAR ENGINEERING > 1. Journal Articles
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