Rapid identification of methylglyoxal trapping constituents from onion peels by pre-column incubation method
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Ji Hoon | - |
dc.contributor.author | Kim, Myeong Il | - |
dc.contributor.author | Syed, Ahmed Shah | - |
dc.contributor.author | Jung, Kiwon | - |
dc.contributor.author | Kim, Chul Young | - |
dc.date.accessioned | 2021-06-22T15:23:21Z | - |
dc.date.available | 2021-06-22T15:23:21Z | - |
dc.date.created | 2021-01-22 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.issn | 1226-3907 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/11621 | - |
dc.description.abstract | The methylglyoxal (MGO) trapping constituents from onion (Allium cepa L.) peels were investigated using pre-column incubation of MGO and crude extract followed by HPLC analysis. The peak areas of MGO trapping compounds decreased, and their chemical structures were identified by HPLC-ESI/MS. Among major constituents in outer scale of onion, 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone (2) was more effective MGO scavenger than quercetin (6) and its 4′-glucoside, spiraeoside (3). After 1 h incubation, compound 2 trapped over 90% MGO at a concentration of 0.5 mM under physiological conditions, but compounds 3 and 6 scavenged 45%, 16% MGO, respectively. HPLC-ESI/MS showed that compound 2 trapped two molecules of MGO to form a di-MGO adduct and compounds 3 and 6 captured one molecule of MGO to form mono-MGO adducts, and the positions 6 and 8 of the A ring of flavonoids were major active sites for trapping MGO. © 2017, Korean Society of Pharmacognosy. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Korean Society of Pharmacognosy | - |
dc.title | Rapid identification of methylglyoxal trapping constituents from onion peels by pre-column incubation method | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Chul Young | - |
dc.identifier.doi | 10.20307/nps.2017.23.4.247 | - |
dc.identifier.scopusid | 2-s2.0-85041037260 | - |
dc.identifier.bibliographicCitation | Natural Product Sciences, v.23, no.4, pp.247 - 252 | - |
dc.relation.isPartOf | Natural Product Sciences | - |
dc.citation.title | Natural Product Sciences | - |
dc.citation.volume | 23 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 247 | - |
dc.citation.endPage | 252 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002294534 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordPlus | 2 (3,4 dihydroxybenzoyl) 2,4,6 trihydroxy 3 benzofuranone | - |
dc.subject.keywordPlus | 3 benzofuranone derivative | - |
dc.subject.keywordPlus | flavonoid | - |
dc.subject.keywordPlus | methylglyoxal | - |
dc.subject.keywordPlus | quercetin | - |
dc.subject.keywordPlus | spiraeoside | - |
dc.subject.keywordPlus | unclassified drug | - |
dc.subject.keywordPlus | Article | - |
dc.subject.keywordPlus | chemical structure | - |
dc.subject.keywordPlus | concentration response | - |
dc.subject.keywordPlus | electrospray mass spectrometry | - |
dc.subject.keywordPlus | high performance liquid chromatography | - |
dc.subject.keywordPlus | incubation time | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | onion | - |
dc.subject.keywordPlus | reaction time | - |
dc.subject.keywordAuthor | Allium cepa L | - |
dc.subject.keywordAuthor | Flavonoids | - |
dc.subject.keywordAuthor | Methylglyoxal trapping | - |
dc.subject.keywordAuthor | Pre-column incubation | - |
dc.identifier.url | https://synapse.koreamed.org/articles/1060675 | - |
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