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In vitro Evaluation of Carbon-Based Nanospheres as Drug Delivery Vesicles in Breast Cancer Cell
- Issue Date
- Feb-2020
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- Carbon nanosphere; Drug-delivery; In-vitro study; Cytotoxicity
- Citation
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.41, no.2, pp 112 - 116
- Pages
- 5
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Volume
- 41
- Number
- 2
- Start Page
- 112
- End Page
- 116
- ISSN
- 0253-2964
1229-5949
- Abstract
- The application of nanoparticles in cancer treatment allows precise tumor treatment by enhancing drug delivery to the tumor area. To overcome limitations in the drug delivery system, we report carbon-based nanospheres (CSs) that have high drug loading capacity as well as anti-cancer effects. Monodisperse and size-tunable (170-583 nm) CSs with excellent surface area up to 2619 m(2)/g provided high drug loading capacity in four different types of drugs (doxorubicin, gemcitabine, docetaxel, and paclitaxel), and demonstrated strong anti-cancer effects against MDA-MB-231 human breast carcinoma cells.
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Related Researcher
- yoo, won cheol
- ERICA 공학대학 (ERICA 에너지바이오학과)