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Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo
- Authors
- Jeong, Gijin; Lee, Jee-Wook; Gong, Gyeonghyeon; Ko, Hyeji; Choi, Ikjang; Seo, Hyeonglim; Lee, Youngbok; Millward, Niki M. Zacharias; Bhattacharya, Pratip K.
- Issue Date
- Apr-2016
- Publisher
- ELSEVIER SCIENCE INC
- Keywords
- Hyperpolarization; Dynamic nuclear polarization; MR spectroscopy and imaging; In vivo metabolic MR
- Citation
- JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.36, pp 224 - 228
- Pages
- 5
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
- Volume
- 36
- Start Page
- 224
- End Page
- 228
- ISSN
- 1226-086X
1876-794X
- Abstract
- We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition, we describe our initial two slice selective spectroscopy in vivo experiments in mice. These techniques along with advances by other laboratories will allow for multiple metabolic pathways to be imaged in real-time and in vivo. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
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Related Researcher
- lee, young bok
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY (DEPARTMENT OF CHEMICAL AND MOLECULAR ENGINEERING)