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Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation

Authors
Bae, Hyoung EunMortensen, Jonas S.Ribeiro, OrquideaDu, YangEhsan, MuhammadKobilka, Brian K.Loland, Claus J.Byrne, BernadetteChae, Pil Seok
Issue Date
2016
Publisher
Royal Society of Chemistry
Citation
Chemical Communications, v.52, no.81, pp.12104 - 12107
Indexed
SCIE
SCOPUS
Journal Title
Chemical Communications
Volume
52
Number
81
Start Page
12104
End Page
12107
URI
https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/16041
DOI
10.1039/c6cc06147h
ISSN
1359-7345
Abstract
A novel class of detergents, designated tandem neopentyl glycol maltosides (TNMs), were evaluated with four target membrane proteins. The best detergent varied depending on the target, but TNM-C12L and TNM-C11S were notable for their ability to confer increased membrane protein stability compared to DDM. These agents have potential for use in membrane protein research.
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COLLEGE OF ENGINEERING SCIENCES > DEPARTMENT OF BIONANO ENGINEERING > 1. Journal Articles

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ERICA 공학대학 (DEPARTMENT OF BIONANO ENGINEERING)
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