Detailed Information
Cited 0 time in 
Cited 0 time in 
Cited 0 time in
Metadata Downloads
Thieny/Furanyl-hydroxyphenylpropenones as Inhibitors of LPS-induced ROS and NO Production in RAW 264.7 Macrophages, and Their Structure-Activity Relationship Studyopen access
- Issue Date
- Aug-2014
- Publisher
- KOREAN CHEMICAL SOC
- Keywords
- Thieny/Furanyl-hydroxyphenylpropenones; LPS-induced ROS and NO; Inhibition; Structure-activity relationship study
- Citation
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.35, no.8, pp 2481 - 2486
- Pages
- 6
- Indexed
- SCI
SCIE
SCOPUS
KCI
- Journal Title
- BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Volume
- 35
- Number
- 8
- Start Page
- 2481
- End Page
- 2486
- ISSN
- 0253-2964
1229-5949
- Abstract
- Twelve thienyl/furanyl-hydroxyphenylpropenones were Systematically designed and synthesized, and evaluated for their inhibitory effect on LPS-induced ROS and NO production in RAW 264.7 macrophages. Compound 11 displayed the most significant inhibitory activity of LPS-induced ROS and NO production in RAW 264.7 macrophages. Structure-activity relationship study indicated that para-hydroxyphenyl moiety plays an important role for inhibitory activities on both LPS-induced ROS and NO production as well as 3-thienyl moiety on molecule.
- Files in This Item
- Appears in
Collections - COLLEGE OF PHARMACY > DEPARTMENT OF PHARMACY > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
Related Researcher
- Nam, Tae gyu
- COLLEGE OF PHARMACY (DEPARTMENT OF PHARMACY)