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Porous Three-Dimensional PVA/Gelatin Sponge for Skin Tissue Engineering

Authors
Choi, Soon MoSingh, DeeptiKumar, AshokOh, Tae HwanCho, Yong WooHan, Sung Soo
Issue Date
Mar-2013
Publisher
TAYLOR & FRANCIS AS
Keywords
Compression; 3-D sponge; freeze-drying; gelatin; human fibroblast; PVA; skin tissue engineering
Citation
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, v.62, no.7, pp.384 - 389
Indexed
SCIE
SCOPUS
Journal Title
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Volume
62
Number
7
Start Page
384
End Page
389
URI
https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/28798
DOI
10.1080/00914037.2012.710862
ISSN
0091-4037
Abstract
A series of PVA/gelatin scaffolds in different concentrations were prepared and blended to evaluate the polymer concentration effects on the architecture of the scaffold. SEM images revealed that with increasing gelatin concentration the average pore diameters varied from 60 to 190nm. Bio-compatibility assay showed cells attached and elongated actively on the scaffolds and cyto-toxicity results of all samples were found to be in grade 1 or 0, indicating the bio-safety of PVA/gelatin as biomaterial. Results indicate the polymer concentration effects on the architecture of the scaffold and PVA/gelatin macroporous scaffolds have potential to be bio-matrices for tissue genesis.
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Cho, Yong Woo
ERICA 공학대학 (DEPARTMENT OF MATERIALS SCIENCE AND CHEMICAL ENGINEERING)
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