Anti-inflammatory properties of a triterpenoidal glycoside from Momordica cochinchinensis in LPS-stimulated macrophages
DC Field | Value | Language |
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dc.contributor.author | Jung, Kiwon | - |
dc.contributor.author | Chin, Young-Won | - |
dc.contributor.author | Yoon, Kee Dong | - |
dc.contributor.author | Chae, Hee-Sung | - |
dc.contributor.author | Kim, Chul Young | - |
dc.contributor.author | Yoo, Hunseung | - |
dc.contributor.author | Kim, Jinwoong | - |
dc.date.accessioned | 2021-06-23T04:04:22Z | - |
dc.date.available | 2021-06-23T04:04:22Z | - |
dc.date.issued | 2013-02 | - |
dc.identifier.issn | 0892-3973 | - |
dc.identifier.issn | 1532-2513 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/28873 | - |
dc.description.abstract | Two triterpenoidal saponins were isolated from the seeds of Momordica cochinchinensis Sprenger (Cucurbitaceae). Identification of chemical structures has been performed by H-1- and C-13-NMR spectroscopy and gas chromatography (GC). One of the saponins is a new gypsogenin glycoside, named as gypsogenin 3-O-beta-D-galactopyranosyl(1 -> 2)-[alpha- L-rhamnopyranosyl(1 -> 3)]-beta-D-glucuronopyranoside (compound 1), which is reported for the first time from natural resources. The other saponin is a quillaic acid glycoside (compound 2), which showed anti-inflammatory activities in RAW 264.7 cells. The mechanistic understanding of anti-inflammatory activities demonstrates that compound 2 inhibits lipopolysaccharide-induced expression of nitric oxide and IL-6 via NF-kappa B pathway. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.title | Anti-inflammatory properties of a triterpenoidal glycoside from Momordica cochinchinensis in LPS-stimulated macrophages | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.3109/08923973.2012.715165 | - |
dc.identifier.scopusid | 2-s2.0-84869171019 | - |
dc.identifier.wosid | 000312505400002 | - |
dc.identifier.bibliographicCitation | IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, v.35, no.1, pp 8 - 14 | - |
dc.citation.title | IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY | - |
dc.citation.volume | 35 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 8 | - |
dc.citation.endPage | 14 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.subject.keywordPlus | NF-KAPPA-B | - |
dc.subject.keywordPlus | GYPSOPHILA-OLDHAMIANA | - |
dc.subject.keywordPlus | SAPONINS | - |
dc.subject.keywordPlus | ROOTS | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | SAPONARIA | - |
dc.subject.keywordPlus | PATHWAY | - |
dc.subject.keywordPlus | SPRENG | - |
dc.subject.keywordAuthor | anti-inflammation | - |
dc.subject.keywordAuthor | Cucurbitaceae | - |
dc.subject.keywordAuthor | gypsogenin glycoside | - |
dc.subject.keywordAuthor | Momordica cochichinensis | - |
dc.subject.keywordAuthor | quillaic acid glycoside | - |
dc.identifier.url | https://www.tandfonline.com/doi/abs/10.1271/bbb.120739 | - |
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