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Tandem Facial Amphiphiles for Membrane Protein Stabilization
- Authors
- Chae, Pil Seok; Gotfryd, Kamil; Pacyna, Jennifer; Miercke, Larry J. W.; Rasmussen, Soren G. F.; Robbins, Rebecca A.; Rana, Rohini R.; Loland, Claus J.; Kobilka, Brian; Stroud, Robert; Byrne, Bernadette; Gether, Ulrik; Gellman, Samuel H.
- Issue Date
- Dec-2010
- Publisher
- American Chemical Society
- Citation
- Journal of the American Chemical Society, v.132, no.47, pp.16750 - 16752
- Indexed
- SCIE
SCOPUS
- Journal Title
- Journal of the American Chemical Society
- Volume
- 132
- Number
- 47
- Start Page
- 16750
- End Page
- 16752
- ISSN
- 0002-7863
- Abstract
- We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.
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Related Researcher
- Chae, Pil Seok
- ERICA 첨단융합대학 (ERICA 바이오나노공학전공)