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Alterations in Differentially Expressed Genes in the Head of Oryzias latipes Following Benzo[a]pyrene Exposure
- Authors
- Oh, Jeong Hwan; Moon, Hyo-Bang; Choe, Eun Sang
- Issue Date
- Jun-2010
- Publisher
- SPRINGER
- Keywords
- Polycyclic aromatic hydrocarbon; Environmental pollutant
- Citation
- BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, v.84, no.6, pp.682 - 686
- Indexed
- SCIE
SCOPUS
- Volume
- 84
- Number
- 6
- Start Page
- 682
- End Page
- 686
- ISSN
- 0007-4861
- Abstract
- Differentially expressed genes (DEGs) in the head of medaka (Oryzias latipes) were investigated to assess the biological effects of benzo[a]pyrene (BaP) on genomic alterations. Eight and ten DEGs were identified in response to short (48 h) and long-term (15 days) exposure to BaP (25 mu g/L), respectively, using annealing control primer-based polymerase chain reaction. Among the DEGs, matrilin 1 and prothrombin were commonly detected, suggesting that BaP exposure can alter the expression of genes associated with the formation of extracellular matrix and blood coagulation in the head of medaka.
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Related Researcher
- Moon, Hyo-Bang
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY (DEPARTMENT OF MARINE SCIENCE AND CONVERGENCE ENGINEERING)