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A small molecule inhibitor of alpha 4 integrin-dependent cell migration

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dc.contributor.authorLee, Jongkook-
dc.contributor.authorHong, Jiyong-
dc.contributor.authorNam, Tae-Gyu-
dc.contributor.authorPeters, Eric C.-
dc.contributor.authorOrth, Anthony P.-
dc.contributor.authorGeierstanger, Bernhard H.-
dc.contributor.authorGoldfinger, Lawrence E.-
dc.contributor.authorGinsberg, Mark H.-
dc.contributor.authorCho, Charles Y.-
dc.contributor.authorSchultz, Peter G.-
dc.date.accessioned2021-06-23T16:02:14Z-
dc.date.available2021-06-23T16:02:14Z-
dc.date.issued2009-02-
dc.identifier.issn0968-0896-
dc.identifier.issn1464-3391-
dc.identifier.urihttps://scholarworks.bwise.kr/erica/handle/2021.sw.erica/41400-
dc.description.abstractA small molecule inhibitor of alpha 4 integrin-dependent cell migration was identified through a cell-based screen of small molecule libraries. Biochemical and cellular experiments suggest that this molecule functions by interacting with gamma-parvin. This molecule should serve as a useful tool to study alpha 4 integrin signaling and may lead to new therapeutics for the treatment of autoimmune diseases. (C) 2008 Elsevier Ltd. All rights reserved.-
dc.format.extent4-
dc.language영어-
dc.language.isoENG-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.titleA small molecule inhibitor of alpha 4 integrin-dependent cell migration-
dc.typeArticle-
dc.publisher.location영국-
dc.identifier.doi10.1016/j.bmc.2008.02.067-
dc.identifier.scopusid2-s2.0-58949098781-
dc.identifier.wosid000262980500006-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY, v.17, no.3, pp 977 - 980-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY-
dc.citation.volume17-
dc.citation.number3-
dc.citation.startPage977-
dc.citation.endPage980-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryBiochemistry & Molecular Biology-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.subject.keywordPlusCOTTON-TOP TAMARIN-
dc.subject.keywordPlusGAMMA-PARVIN-
dc.subject.keywordPlusANTAGONISTS-
dc.subject.keywordPlusANTIBODY-
dc.subject.keywordPlusKINASE-
dc.subject.keywordPlusLIBRARIES-
dc.subject.keywordPlusCOLITIS-
dc.subject.keywordPlusBINDING-
dc.subject.keywordAuthorCOTTON-TOP TAMARIN-
dc.subject.keywordAuthorGAMMA-PARVIN-
dc.subject.keywordAuthorANTAGONISTS-
dc.subject.keywordAuthorANTIBODY-
dc.subject.keywordAuthorKINASE-
dc.subject.keywordAuthorLIBRARIES-
dc.subject.keywordAuthorCOLITIS-
dc.subject.keywordAuthorBINDING-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0968089608001879?via%3Dihub-
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