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Identification of Novel Acetylenic Alcohols and a New Dihydrothiopyranone from the Tropical Sponge Reniochalina sp.
- Authors
- Lee, Hyi-Seung; Lee, Ji Hye; Won, Hoshik; Park, Song-Kyu; Kim, Hwan Mook; Shin, Hee Jae; Park, Heung Sik; Sim, Chung J.; Kim, Hye-Kyeong
- Issue Date
- Jan-2009
- Publisher
- American oil chemists' society Press
- Keywords
- Tropical sponge; Reniochalina sp.; Acetylenic alcohol; Dihydrothiopyranone; Growth inhibition
- Citation
- Lipids, v.44, no.1, pp.71 - 75
- Indexed
- SCOPUS
- Journal Title
- Lipids
- Volume
- 44
- Number
- 1
- Start Page
- 71
- End Page
- 75
- ISSN
- 0024-4201
- Abstract
- Two new acetylenic alcohols (1-2) and a new dihydrothiopyranone (3) were isolated from the tropical sponge Reniochalina sp. Their structures were determined by spectroscopic and chemical methods to be (3R)-hydroxyoctatriacont-(4E)-en-1-yne (1), 5-hydroxyheptatriacont-(3Z)-en-1-yne (2) and 2-hexadecyl-2,3-dihydrothiopyran-4-one (3). The acetylenic alcohol (1) exhibited significant growth inhibitory effect against human tumor cell lines.
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Related Researcher
- Won, Ho shik
- COLLEGE OF SCIENCE AND CONVERGENCE TECHNOLOGY (DEPARTMENT OF CHEMICAL AND MOLECULAR ENGINEERING)