Fabrication of bio-composite drug delivery system using rapid prototyping technology
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chu, Won-Shik | - |
dc.contributor.author | Kim, Sung-Geun | - |
dc.contributor.author | Kim, Hyung-Jung | - |
dc.contributor.author | Lee, Caroline S. | - |
dc.contributor.author | Ahn, Sung-Hoon | - |
dc.date.accessioned | 2021-06-23T20:43:11Z | - |
dc.date.available | 2021-06-23T20:43:11Z | - |
dc.date.issued | 2007-00 | - |
dc.identifier.issn | 1013-9826 | - |
dc.identifier.issn | 1662-9795 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/44331 | - |
dc.description.abstract | The rapid prototyping (RP) technology has advanced in various fields such as verification of design, and functional test. Recently, researchers have studied bio-materials to fabricate functional bio-RP parts. In this research, a nano composite deposition system (NCDS) was developed to fabricate three-dimensional functional parts for bio-applications. In the hybrid process, the material removal process by mechanical micro machining and/or the deposition process are combined. NCDS uses biocompatible or biodegradable polymer resin as matrix and various bio-ceramics to form bio-composite materials. To test drug release rate in vivo environment, two different types of drug delivery system (DDS) were fabricated using the bio-composite materials. 1) Container type DOS used poly(DL-lactide-co-glycolide acid)(50:50) and 5-fluorouracil as the drug composite while polycaprolactone(PCL) served as the container of the drug. 2) Scaffold type DDS formed porous microstructure with poly(DL-lactide-co-glycolide acid)(50:50) and 5-fluorouracil composite. The effect of geometry of the DDS on release rate of drug is under investigation. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Trans Tech Publications Ltd | - |
dc.title | Fabrication of bio-composite drug delivery system using rapid prototyping technology | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.4028/www.scientific.net/KEM.342-343.497 | - |
dc.identifier.scopusid | 2-s2.0-34147093304 | - |
dc.identifier.wosid | 000246657900125 | - |
dc.identifier.bibliographicCitation | Key Engineering Materials, v.342-343, pp 497 - 500 | - |
dc.citation.title | Key Engineering Materials | - |
dc.citation.volume | 342-343 | - |
dc.citation.startPage | 497 | - |
dc.citation.endPage | 500 | - |
dc.type.docType | Conference Paper | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Ceramics | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Biomaterials | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Composites | - |
dc.subject.keywordPlus | Bioceramics | - |
dc.subject.keywordPlus | Biocompatibility | - |
dc.subject.keywordPlus | Biodegradable polymers | - |
dc.subject.keywordPlus | Drug products | - |
dc.subject.keywordPlus | Nanocomposites | - |
dc.subject.keywordPlus | Rapid prototyping | - |
dc.subject.keywordPlus | 5-fluorouracil | - |
dc.subject.keywordPlus | Biocomposites | - |
dc.subject.keywordPlus | Drug composites | - |
dc.subject.keywordPlus | Drug delivery system (DDS) | - |
dc.subject.keywordPlus | Drug delivery | - |
dc.subject.keywordAuthor | Bio-composite | - |
dc.subject.keywordAuthor | Biodegradable | - |
dc.subject.keywordAuthor | Drug delivery system (DDS) | - |
dc.subject.keywordAuthor | Rapid prototyping | - |
dc.identifier.url | https://www.scientific.net/KEM.342-343.497 | - |
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